It sounds like you're facing a codec compatibility issue with Windows 10 and the Adobe suite. When rendering H.265 with NVIDIA HEVC, some compatibility hiccups can occur, especially with MP4 or AVI formats. It's not uncommon; I've seen similar issues in various forums. MKV format generally has better support for H.265, which is likely why you're not facing issues there.
For handling MP4 formats I've been using Movavi. Pretty easy to use and reliable option. See more about it and other alternatives in this article: https://www.movavi.com/imovie-for-windows/.